Treatment of juvenile idiopathic arthritis. Golimumab in Juvenile Idiopathic Arthritis-associated Uveitis Failing Adalimumab

Conținutul

    DOI: We examined 16 patients with s-JIA and reported the clinical manifestations, laboratory data, treatments and outcomes.

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    We retrospectively reviewed their medical charts. Results: There were nine boys and seven girls, with mean age of onset of 7.

    Tema plagiatului este tot mai mult discutată în ultima vreme. Apariția unor programe performante de căutare și identificare a similitudinilor între texte [ Hypertrophic osteoarthropathy HOA is a rare, hereditary disease characterized by clubbing and new bone formation in the periosteal region that may be associated with joint pain, cutaneous abnormalities, seborrhea or hyperhydrosis. Juvenile idiopathic arthritis JIA is one of the most frequent chronic diseases with childhood onset, patients develop inflammatory joint pain and extra-articular manifestations with imunologic substrate.

    One patient had Epstein-Barr virus-associated hemophagocytic syndrome complications. Neutrophilic leukocytosis was a common feature.

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    Other laboratory data showed elevated C-reactive protein levels The mean time from onset of symptoms to diagnosis was 9. Non-steroidal anti-inflammatory drugs, steroids, disease-modifying anti-rheumatic drugs and anti-tumor necrosis factor agents were used for treatment.

    Due to prolonged fever, 2. Most cases had satisfactory therapeutic outcomes except one boy, who had permanent joint contracture.

    Conclusion: The clinical manifestations of s-JIA in Taiwan were often accompanied by a prolonged fever.

    Doi pacienţi cu artrită juvenilă idiopatică au dezvoltat o infecţie cu varicelă însoţită de semne şi simptome de meningită aseptică, care s- a remis fără sechele. The types and proportion of adverse events in juvenile idiopathic arthritis patients were similar to those seen in trials of Enbrel in adult patients with rheumatoid arthritis, and the majority were mild. Tipurile şi proporţia evenimentelor adverse întâlnite la pacienţii cu artrită juvenilă idiopatică au fost similare cu cele observate în cadrul studiilor cu Enbrel, la pacienţi adulţi cu poliartrită reumatoidă, majoritatea fiind uşoare. For polyarticular juvenile idiopathic arthritis, Humira was compared with placebo, alone or as an add- on to methotrexate, in one main study involving patients aged between four and 17 years.

    This results in clinicians often suspecting bacterial infections and prescribing several kinds of antibiotics. In the case of prolonged fever, s-JIA should always be placed on the list of differential diagnoses. Copyright © Taiwan Society of Microbiology.

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